Dobutamine - Wikipedia
Dobutamine is a direct-acting agent whose primary activity results from stimulation of the β 1 -adrenoceptors of the heart, increasing contractility and cardiac output. Since it does not act on dopamine receptors to inhibit the release of norepinephrine (another α 1 agonist), dobutamine is less prone to induce hypertension than is dopamine.
Dobutamine - StatPearls - NCBI Bookshelf
Feb 23, 2024 · Dobutamine is approved by the US Food and Drug Administration (FDA) for short-term use in patients with decreased contractility due to heart failure or cardiac procedures resulting in cardiac decompensation.
Dobutamine: Uses, Interactions, Mechanism of Action - DrugBank …
Dobutamine is a beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Dobutamine Uses, Side Effects & Warnings - Drugs.com
Aug 14, 2023 · Dobutamine is used short-term to treat cardiac decompensation due to weakened heart muscle. Dobutamine is usually given after other heart medicines have been tried without success. Dobutamine may also be used for purposes not listed in this medication guide.
Dobutamine (Dobutrex): Uses & Side Effects - Cleveland Clinic
Dobutamine is a medication that treats heart failure by strengthening your heart muscle. Heart failure happens when your heart isn’t pumping very well. A healthcare provider will give you this injection in a hospital or clinic setting. The brand name of dobutamine is Dobutrex®. What is this medication? DOBUTAMINE (DOE byoo tah meen) is an inotrope.
Dobutamine: Side Effects, Uses, Dosage, Interactions, Warnings - RxList
Mar 22, 2023 · What Is Dobutamine and How Does It Work? Dobutamine is a prescription medication indicated for cardiac decompensation. Dobutamine is available under the following different brand names: Dobutrex. What Are the Side Effects Associated with Using Dobutamine? Common side effects of Dobutamine include: Serious side effects of Dobutamine include:
dobutamine (Rx) - Medscape Drugs & Diseases
Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron....
DOBUTamine: Dosage, Mechanism/Onset of Action, Half-Life
Feb 17, 2020 · Dobutamine, a racemic mixture, stimulates myocardial beta 1 -adrenergic receptors primarily by the (+) enantiomer and some alpha 1 receptor agonism by the (-) enantiomer, resulting in increased contractility and heart rate, and stimulates both beta 2 - and alpha 1 -receptors in the vasculature.
Dobutamine (Dobutamine): Side Effects, Uses, Dosage ... - RxList
Mar 22, 2023 · Dobutamine Injection is a catecholamine indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of adults with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures. Dobutamine is available in generic form.
Dobutamine | C18H23NO3 | CID 36811 - PubChem
Dobutamine is a direct-acting inotropic agent whose primary activity results from stimulation of the beta-adrenoceptors of the heart while producing comparatively mild chronotropic, hypertensive, arrhythmogenic, and vasodilative effects. Dobutamine acts primarily on beta-1 adrenergic receptors, with negligible effects on beta-2 or alpha receptors.