Vascular Model Repository
A library of computational models of normal and diseased cardiovascular models. Academic, government and industry researchers. Our models can be used to verify computational methods for fluid and solid mechanics.
Coronary Vasculature Models | Atlas of Human Cardiac Anatomy
We have created models of the cardiac venous system and the coronary arteries using methods described in the Static Imaging Methodologies section. Using Mimics Software (Materialise, Leuven, Belgium) we can segment out the vasculature by highlighting the …
In Vitro Strategies to Vascularize 3D Physiologically Relevant Models
In the last decade, the fabrication of vascularized physiologically relevant 3D constructs has been attempted by numerous tissue engineering strategies, which are classified here in microfluidic technology, 3D coculture models, namely, spheroids and organoids, and biofabrication.
Vascularization Strategies in 3D Cell Culture Models: From Scaffold ...
2022年11月23日 · Vascularization refers to the process of formation of blood vessels within a structure, ensuring cellular proliferation. Vasculature ensures the sufficient supply of oxygen and nutrients to cells, along with the removal of metabolic wastes in …
Modelling large scale artery haemodynamics from the heart to the …
2024年1月13日 · In this study, we aimed to construct a physiologically possible 3D model of human blood vessels ranging from the aortic root through to the retina, by combining existing subject-specific 3D...
3D bioprinting for modelling vasculature - PMC - PubMed …
2018年10月2日 · In this review, vasculature models printed using extrusion-, droplet-, and laser-based bioprinting techniques are summarized and compared.
Vascular organoids: unveiling advantages, applications, challenges, …
2023年10月10日 · Furthermore, we discuss the diverse applications of vascular organoids and emphasize the importance of incorporating all relevant cellular components in a 3D model to accurately recapitulate vascular pathophysiology.
High-resolution 3D reconstructions of human vasculatures: …
2021年9月1日 · In this study, anatomically accurate models were created from high-resolution images of real patient vasculatures. Using fourteen human cadavers donated for research, we collected high-resolution images to generate 3D computational renderings …
Vascular cells of blood vessels and organs across the human body
2024年12月6日 · The vasculature provides a continuous system of vessels around the human body, comprising an estimated 100,000-km network of arteries, capillaries and veins. ... This paper describes the side ...
From arteries to capillaries: approaches to engineering human vasculature
We discuss engineering human vasculature ranging from large blood vessels to the capillaries. Our focus is on the design criteria, bioengineering approaches, and key challenges for generating mm- to microscale vasculature and transplantable vascularized tissues.
3D Bioprinted Multicellular Vascular Models - PubMed
Here, a new class of nanoengineered hydrogel-based cell-laden bioinks is introduced, that can be printed into 3D, anatomically accurate, multicellular blood vessels to recapitulate both the physical and chemical microenvironments of native human vasculature.
The importance of modeling the human cerebral vasculature in …
2021年1月14日 · We used an anatomically accurate three-dimensional geometry of a 50th percentile U.S. male head that included the skin, eyes, sinuses, spine, skull, brain, meninges, and a detailed network of cerebral vasculature to develop a high-fidelity model.
In Vitro Strategies to Vascularize 3D Physiologically Relevant Models
2021年8月5日 · In the last decade, the fabrication of vascularized physiologically relevant 3D constructs has been attempted by numerous tissue engineering strategies, which are classified here in microfluidic technology, 3D coculture models, namely, spheroids and …
An in vivo model allowing continuous observation of human vascular ...
2021年1月12日 · To understand human vascular biology and translate findings into human research, we need human blood vessel models to replicate human vascular physiology. Here, we show that human tumor tissue...
Geometric Modeling of Vasculature - ScienceDirect
2019年1月1日 · From medical imaging data a variety of image processing, image segmentation, and optimization methods can be utilized to generate accurate geometric models of the vasculature.
Multiscale modeling of human cerebrovasculature: A hybrid …
2020年6月22日 · The cerebral vasculature has a complex and hierarchical network, ranging from vessels of a few millimeters to superficial cortical vessels with diameters of a few hundred micrometers, and to the microvasculature (arteriole/venule) and capillary beds in the cortex.
Silicone Mock Vessels - Biomedical Device Consultants
BDC’s silicone anatomical models can be designed and manufactured to replicate healthy or diseased vasculature. Building from either our in-house patient-based datasets or a dataset provided, the BDC team can create and modify various states of disease, providing the most realistic platform for product evaluation, physician training ...
Multiscale modeling of human cerebrovasculature: A hybrid
2020年6月22日 · This paper presents a multiscale model of human cerebrovasculature based on a hybrid approach that uses image-based geometries and a newly developed mathematical algorithm.
The importance of modeling the human cerebral vasculature in blunt ...
2021年1月14日 · We used an anatomically accurate three-dimensional geometry of a 50th percentile U.S. male head that included the skin, eyes, sinuses, spine, skull, brain, meninges, and a detailed network of cerebral vasculature to develop a high-fidelity model.
Model Systems to Study the Mechanism of Vascular Aging - MDPI
2023年10月19日 · To study vascular aging, various models are available, ranging from in vivo mouse studies to cell culture options, and there are also microfluidic in vitro model systems known as vessels-on-a-chip. Together, these models offer …
Editorial: Mechanotransduction in vascular development and disease
5 天之前 · Thus, there is increasing interest to model hemodynamics and vessel structure/function in organoids. ... Moving onto the cerebral vasculature, the review by Dmytriv et al. discusses the onset and progression of cognitive impairment associated with chronic vascular encephalopathy (CVE). CVE occurs after prolonged reduction of blood flow to the ...
The importance of modeling the human cerebral vasculature in blunt ...
2021年1月14日 · We performed blunt trauma simulations and determined the intracranial pressure (ICP), the relative displacement (RD), the von Mises stress, and the maximum principal strain. We validated our detailed-vasculature model by comparing the model-predicted ICP and RD values with experimental measurements.