Hepatic vagal afferents convey clock-dependent signals to
2024年11月7日 · We report that liver molecular clock dysfunction is signaled to the brain through the hepatic vagal afferent nerve (HVAN), leading to altered food intake patterns that are …
The metabolic role of vagal afferent innervation - Nature
2018年9月5日 · Vagal afferent nerve terminals innervate layers of the gastrointestinal wall to sense nutrient-related hormonal and/or mechanical signals and trigger neuronal transmission …
Vagal sensory neurons and gut-brain signaling - PMC
Vagal afferents form different terminal endings in the gut, including direct synapses with some enteroendocrine cells named neuropods. Vagal sensory neurons monitor ingested nutrients …
Vagal Afferent Innervation of the Airways in Health and Disease
Alterations in the sensitivity and neurochemical phenotype of vagal afferent nerves and/or the neural pathways that they innervate occur in a wide variety of pulmonary diseases, and as …
Dissecting the Role of Subtypes of Gastrointestinal Vagal Afferents
2020年6月11日 · Gastrointestinal (GI) vagal afferents convey sensory signals from the GI tract to the brain. Numerous subtypes of GI vagal afferent have been identified but their individual …
An Atlas of Vagal Sensory Neurons and Their Molecular …
2019年5月21日 · Here, we present a comprehensive identification, classification, and validation of the neuron types in the neural crest (jugular) and placode (nodose) derived vagal ganglia by …
Sensory Neurons that Detect Stretch and Nutrients in the …
2016年6月30日 · One small group of vagal afferents marked by expression of the receptor GPR65 (∼230 neurons per ganglion) innervates villi in the proximal small intestine close to the gastro …
Sensory representation and detection mechanisms of gut …
2022年1月26日 · Gut hypotonic stimuli activate a dedicated vagal population distinct from mechanical-, hypertonic- or nutrient-sensitive neurons. We demonstrate that hypotonic …
Neuroanatomy of visceral nociception: vagal and splanchnic afferent - Gut
Vagal afferents convey predominantly physiological information while spinal afferents are able to encode noxious events. Because of the different response profiles following activation of these …
The Molecular Diversity of Vagal Afferents Revealed - Cell Press
2019年8月14日 · Using single-cell RNA sequencing (RNA-seq), Kupari and coworkers (Cell Rep., 2019) have generated a long sought-after molecular atlas of vagal afferents in the mouse. …