Spiral Waves in the Heart - SpringerLink
2019年4月5日 · Onset of spiral waves in the heart causes cardiac arrhythmias characterized by extremely fast and irregular heartbeat and can lead to cardiac arrest and sudden cardiac death. Although a general idea about the existence of spiral waves in the heart was proposed a long time ago, only recently it became possible to record them in experiment.
Researchers map rotating spiral waves in live human hearts
2022年9月7日 · Spiral wave breakup: Optical mapping in an explanted human heart shows the transition from ventricular tachycardia to ventricular fibrillation and self-termination.
Dissolution of spiral wave’s core using cardiac optogenetics
2023年12月7日 · Rotating spiral waves in the heart are associated with life-threatening cardiac arrhythmias such as ventricular tachycardia and fibrillation. These arrhythmias are treated by a process called defibrillation, which forces electrical resynchronization of the heart tissue by delivering a single global high-voltage shock directly to the heart.
Control of spiral waves in myocardial tissue by optogenetics and ...
2024年7月27日 · One of the most effective methods to clinically eliminate spiral waves in myocardial tissue is high-voltage defibrillation. This approach involves applying high-intensity electrical voltage to the heart to terminate membrane potential of all cardiomyocyte, effectively eradicating the spiral waves [27].
Researchers Map Rotating Spiral Waves in Live Human Hearts
2022年9月7日 · The researchers published their latest findings, “Direct observation of a stable spiral wave reentry in ventricles of a whole human heart using optical mapping for voltage and calcium” and “Spiral wave breakup: Optical mapping in an explanted human heart shows the transition from ventricular tachycardia to ventricular fibrillation and ...
Spatially Conserved Spiral Wave Activity During Human Atrial ...
2024年2月13日 · In this study, we examined 60 s intracardiac recordings in patients with AF in whom spiral waves were intermittently present at a particular spatial location. We focused on both the most prominent CCW and CW rotating spiral wave and identified the time intervals in which the tips started at the conserved location and could be continuously followed.
Researchers map rotating spiral waves in live human hearts
Researchers at Georgia Tech and clinicians at Emory University School of Medicine are bringing a new understanding to these complicated conditions with the first high-resolution visualizations of stable spiral waves in human ventricles.
The transient outward potassium current plays a key role in spiral wave ...
2021年2月10日 · Spiral wave reentry as a mechanism of lethal ventricular arrhythmias has been widely demonstrated in animal experiments and recordings from human hearts. It has been shown that in structurally normal hearts spiral waves are unstable, breaking up into multiple wavelets via dynamical instabilities.
Spiral Wave - an overview | ScienceDirect Topics
In the heart, both two-dimensional spiral waves and three-dimensional scroll waves have been implicated in the mechanisms of reentry in atrial and VT and fibrillation. 19 Monomorphic VT results when the spiral wave is anchored within the ventricular myocardium and cannot drift away from its origin. In contrast, a polymorphic VT, such as the ...
(PDF) Spiral waves and the heart - ResearchGate
1996年3月1日 · Disorders in the heart's conduction system can lead to the formation of rotating spiral waves, and terminating the re-entrant seeds is crucial to restore cardiac function.
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