Biochemistry and Diseases Related to the Interconversion of ...
2024年10月6日 · This paper discusses the role of enzymes involved in the interconversion of phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine, specifically phosphatidylethanolamine N-methyltransferase (PEMT), phosphatidylserine synthases (PTDSS1 and PTDSS2), and phosphatidylserine decarboxylase (PISD), with a focus on their biochemical ...
The critical role of phosphatidylcholine and phosphatidylethanolamine …
2017年9月1日 · Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co-workers performed groundbreaking research that established the general outline of many of the pathways of phospholipid biosynthesis.
The non-enzymatic oxidation of phosphatidylethanolamine and ...
2024年8月4日 · Phosphatidylethanolamine (PE) and phosphatidylserine (PS), along with phosphatidylcholine (PC), are key phospholipids (PL) in cell membranes and lipoproteins, prone to oxidative modifications. Their oxidized forms, OxPE and OxPS, play significant roles in inflammation and immune response.
The ratio of phosphatidylcholine to phosphatidylethanolamine influences ...
2006年5月1日 · Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are major phospholipids in mammalian membranes. In liver, PC is synthesized via the choline pathway or by methylation of PE via phosphatidylethanolamine N -methyltransferase (PEMT).
Phospholipid Membrane Transport and Associated Diseases
Here, it is converted to phosphatidylethanolamine (PE) by phosphatidylserine decarboxylase proenzyme (PISD), a protein located in the mitochondrial membrane. PE is then transferred to ER, where is converted to PC or PS, depending on the enzyme implicated, phosphatidylethanolamine N -methyltransferase (PEMT), or phosphatidylserine synthase 2 ...
Chapter 1 Phosphatidylserine, phosphatidylethanolamine and ...
1982年1月1日 · This chapter describes the metabolism of phosphatidylcholine, lysophosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine in mammalian cells. There are two established pathways for the biosynthesis of phosphatidylserine, a phospholipid, which accounts for 5–10% of the total phospholipid in eukaryotic cells.
Phosphatidylethanolamine - Wikipedia
Biosynthesis of various phospholipids (including phosphatidylethanolamine) in bacteria. Phosphatidylethanolamine (PE) is a class of phospholipids found in biological membranes. [1] They are synthesized by the addition of cytidine diphosphate-ethanolamine to diglycerides, releasing cytidine monophosphate.
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by …
2015年11月18日 · Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant glycerophospholipids in eukaryotes 1, 2. Besides their roles as main structural components of all cellular...
Effect of phosphatidylcholine, phosphatidylethanolamine and ...
This study examined the effects of phosphatidylcholine on the blood coagulation system using liposomes containing varying concentrations of phosphatidylcholine in the presence of phosphatidylserine at a constant concentration.
Effect of phosphatidylcholine, phosphatidylethanolamine and ...
The results showed suppression of the system by phosphatidylcholine and phosphatidylethanolamine and acceleration by lysophosphatidylcholine. The results of the present study suggest that the cell membrane, the 'location' of blood coagulation, is one of the regulatory factors, and that changes in phosphatidylcholine content and phospholipid ...