Phenolphthalein Laxatives and Risk of Cancer - Oxford Academic
2000年12月6日 · Phenolphthalein was the main component in numerous over-the-counter laxatives, including Ex-Lax and Feen-A-Mint, for most of the 20 th century. The U.S. Food and …
Phenolphthalein's Laxative Effects: A Comprehensive Guide
2024年8月1日 · Phenolphthalein is a laxative that works by increasing intestinal movement, facilitating the passage of stool. It is typically used to treat constipation, chronic atonic or …
Movement Away From Phenolphthalein in Laxatives - JAMA
2009年5月6日 · Phenolphthalein was formally banned by the Food and Drug Administration as an ingredient in over-the-counter laxatives in 1999 due to concerns of possible carcinogenicity. …
Phenolphthalein: Uses, Interactions, Mechanism of Action
2007年9月11日 · Phenolphthalein is a drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. Phenolphthalein was withdrawn in Canada due to …
Phenolphthalein - Wikipedia
Phenolphthalein is described as a stimulant laxative. [16] In addition, it has been found to inhibit human cellular calcium influx via store-operated calcium entry (SOCE, see Calcium release …
Phenolphthalein - 15th Report on Carcinogens - NCBI Bookshelf
2021年12月21日 · The typical oral dose of phenolphthalein as an over-the-counter laxative was 30 to 200 mg for adults and children aged 12 years or older; the recommended dose was not …
Phenolphthalein - an overview | ScienceDirect Topics
Since that time, it had been used as an active ingredient in many over-the-counter (OTC) laxatives drugs. Its initial effects start after 6–8 h and may continue 3–4 days, which suggested …
Preclinical experimental models for assessing laxative activities of ...
Phenolphthalein had been used to treat chronic constipation due to its stimulant laxative activity . The drug affects production of eicosanoids and acts on the Na + /K + -ATPase pump on the …
Phenolphthalein - an overview | ScienceDirect Topics
Phenolphthalein is used in toys as a component of disappearing inks and has been commonly used as a laxative. Phenolphthalein is synthesized by condensation of phthalic anhydride with …
Cathartics and Laxatives General Statement (Monograph) - Drugs.com
Stimulant laxatives mainly promote evacuation of the colon; however, castor oil and phenolphthalein (laxatives containing phenolphthalein are no longer commercially available in …