Lipoprotein - Metabolism - Exogenous Pathway - LiquiSearch
Epithelial cells lining the small intestine readily absorb lipids from nutritive substances. These lipids, including triglycerides, phospholipids, and cholesterol, are assembled with apolipoprotein B-48 into chylomicrons.
LimeMap: a comprehensive map of lipid mediator metabolic …
2021年1月27日 · Lipid Mediator Metabolic Pathway Map (LimeMap), which maps lipid mediators and related metabolites of ω3-FA and ω6-FA origin onto the metabolic pathway with relevant enzymes and receptors, has...
Cholesterol Metabolism | Physiology - Geeky Medics
2010年11月11日 · A brief overview of cholesterol metabolism including types of lipoproteins, exogenous pathway, endogenous pathway and the reverse cholesterol transport pathway.
Mechanisms of Abnormal Lipid Metabolism in the Pathogenesis …
2024年8月2日 · Recent research has linked abnormalities in lipid metabolism to the onset and progression of the disease. Additionally, pathological studies have revealed that ectopic adipose tissue surrounds the β cells in the pancreatic islets, exacerbating the …
Lipid and Lipoprotein Metabolism - PubMed
The exogenous lipoprotein pathway starts with the incorporation of dietary lipids into chylomicrons in the intestine. Chylomicron triglycerides are metabolized in muscle and adipose tissue and chylomicron remnants are formed, which are removed by the liver. The endogenous lipoprotein pathway begins …
Receptor-Mediated ER Export of Lipoproteins Controls Lipid …
Newly synthesized protein and lipid cargos embark on the secretory pathway via COPII-coated vesicles, assembled by the GTPase SAR1 on the endoplasmic reticulum (ER), but how lipid-carrying lipoproteins are distinguished from the general protein cargos in the ER and selectively secreted has not been clear.
Lipid metabolism. The exogenous pathway involves the …
The reverse cholesterol pathway involves the transport of the excess of lipids in the extra-hepatic tissues back to the liver in HDL.
Lipid metabolism - ScienceDirect
2013年6月1日 · Their principal function is to transport exogenous lipids (re-synthesized in the gut from dietary fats), and endogenous lipids (synthesized in the liver) from these sites of synthesis to peripheral sites of utilization (e.g. oxidation in muscle, incorporation in membranes or as precursors of biologically active metabolites) and storage (e.g ...
The role of the exogenous pathway in hypercholesterolaemia
2001年6月1日 · In the exogenous pathway, cholesterol from dietary and biliary sources is absorbed in the intestine and ultimately enters the circulation as a component of chylomicrons. A new class of drugs, the selective cholesterol absorption inhibitors, offers a different approach to current strategies available for the management of hypercholesterolaemia.
An Overview of Lipid Metabolism | SpringerLink
2023年4月29日 · In this chapter, we provide a brief overview of lipid metabolism with a focused discussion and review of lipoproteins, endogenous and exogenous lipid metabolism, and HDL metabolism and reverse cholesterol transport.