突触效能的长时程增强（LTP）和抑制（LTD） | 学习和记忆
2021年6月21日 · 在ca3->ca1突触中，突触后膜上有很多的nmda受体通道和ampa受体通道，尤其是nmda受体通道在ltp和ltd中起了关键作用。 NMDA受体和AMPA受体 现在介绍一下AMPA受 …
Mechanism underlying hippocampal long-term potentiation …
2020年9月7日 · NMDA (N-methyl-D-aspartate) receptor-dependent long-term potentiation (LTP) and long-term depression (LTD) of signal transmission in excitatory neurons, such as …
突触可塑性 Synaptic Plasticity: LTP - 知乎 - 知乎专栏
Schaffer Collaterals pathway的LTP依赖于突触后膜的NMDA受体，通过APV抑制NMDA后无法引导出这种LTP。 NMDA受体的激活激活了下游一系列的信号级联反应产生了这种LTP。
NMDA receptor-dependent long-term potentiation and long …
2012年6月1日 · Long-term potentiation and long-term depression (LTP/LTD) can be elicited by activating N-methyl-d-aspartate (NMDA)-type glutamate receptors, typically by the coincident …
NMDA receptor trafficking in synaptic plasticity and ... - Nature
Emerging evidence indicates that activity-dependent insertion and retrieval of NMDARs to and from synaptic sites mediates some forms of long-term potentiation (LTP) and long-term …
Activation Mechanisms of the NMDA Receptor - Biology of the NMDA …
This phenomenon underlies the paradigm of long-term potentiation (LTP) discovered in 1973 by Bliss and Lomo in which a short burst of high frequency synaptic input (15 Hz for 15 sec or …
Is plasticity of synapses the mechanism of long-term memory …
2019年7月2日 · Glutamate receptors have been of most interest as their ligand, the amino acid glutamate, is the predominant excitatory neurotransmitter in the mammalian nervous system. …
Synaptic plasticity of NMDA receptors: mechanisms and functional ...
Beyond their well-established role as triggers for LTP and LTD of fast synaptic transmission mediated by AMPA receptors, an expanding body of evidence indicates that NMDA receptors …
Expression of NMDA receptor-dependent LTP in the hippocampus…
2013年1月22日 · The view that the expression of N-methyl-D-aspartate (NMDA) receptor-dependent long-term potentiation (LTP) is achieved largely, if not exclusively, by purely …
LTP of AMPA and NMDA Receptor–Mediated Signals: Evidence …
We have addressed the expression of long-term potentiation (LTP) in hippocampal CA1 by comparing AMPA and NMDA receptor–(AMPAR- and NMDAR-) mediated postsynaptic …