Rapid Crystal Dissolution in Gout - Medscape
Deposition of monosodium urate (MSU) crystals is the hallmark of gout. Persistently high serum uric acid (SUA) levels result in MSU crystal deposition not only in joints but also in periarticular ...
Intensive Gout Treatment Meets Urate Goal, Lowers Tophi Burden
2022年11月18日 · At baseline, monosodium urate crystals were detected in joint aspirates in 56% of patients receiving tight control and in 58.5% of those receiving conventional management. The mean serum urate ...
Treatment With Rasburicase of a Tophaceous Gout - Medscape
Monosodium urate crystals are strongly birefringent when observed under polarized light, and negatively birefringent, appearing yellow when parallel, and blue when perpendicular, to the axis of ...
The Lean Antibiotic Mantra - Page 3 - Medscape
2018年4月9日 · The diagnosis was established by aspirating bloody/chalky fluid containing negatively birefringent monosodium urate crystals (Figure 3) from the tophaceous swelling over the second MCP joint. She ...
Febuxostat for Treatment of Chronic Gout - Page 2 - Medscape
[13,16] Criteria included monosodium urate monohydrate crystals in synovial fluid during attack, more than one attack of acute arthritis, maximum inflammation developing within one day, mono ...
White Papules on the Ear - Page 2 - Medscape
2003年7月31日 · The most characteristic lesion of gout is the tophus, a deposit of crystals of monosodium urate that triggers a severe inflammatory reaction in the surrounding tissue. Although the first ...
Urate in Atherosclerotic Plaques Boosts Risk for CV Events
2024年6月3日 · Patients with gout and hyperuricemia harboring cardiovascular (CV) monosodium urate (MSU) deposits in atherosclerotic plaques are at an increased risk for major adverse cardiovascular events (MACE).
Target These Serum Urate Levels to Prevent Gout Flares - Medscape
2024年2月6日 · Gout is caused by monosodium urate crystallization within the joints, which occurs when SU levels exceed the saturation point for uric acid crystallization in the body: approximately 6.8 mg/dL ...
Breastfeeding Primer for PCPs - Page 3 - Medscape
2012年5月16日 · However, the presence of urate crystals has significance only on or after day 5 of life and only in the context of low voids and significant weight loss. Table 1. Infant Output by Age.
Gut Microbiome Has Potential to Counter Gout - Medscape
2024年11月18日 · Researchers have identified separate gut bacteria species that can metabolize purines and urate, suggesting that microbial pathways might be leveraged through probiotics to reduce hyperuricemia.