Circulating apoptotic bodies maintain mesenchymal stem cell …
2018年7月20日 · In this study, we used Fas-deficient MRL/ lpr and Caspase 3−/− mice to show that reduction of apoptotic body formation significantly impaired the self-renewal and osteo …
Enhancer-mediated FOXO3 expression promotes MSC adipogenic ...
2024年2月1日 · In this study, we identified enhancers-mediated gene FOXO3 promoting MSC adipogenic differentiation by activating autophagy. We integrated data of RNA sequencing …
TGF-β/SMAD signaling regulation of mesenchymal stem cells …
2020年1月29日 · Adipocytes arising from mesenchymal stem cells (MSCs) requires MSC adipocyte commitment and differentiation of preadipocytes to mature adipocytes. Several …
Fate decision of mesenchymal stem cells: adipocytes or …
2016年2月12日 · Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered in bone marrow, are multipotent cells capable of differentiating into...
The Role of Reactive Oxygen Species in Mesenchymal Stem Cell Adipogenic …
Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and regenerative medicine. The multipotent stem cell component of MSC isolates is able to …
Adipokines at the crossroads of obesity and mesenchymal stem …
2023年2月7日 · In this review, we aim to discuss the current knowledge on the central role of adipokines in the crosstalk between obesity and MSC dysfunction. We also summarize recent …
How mesenchymal stem cells transform into adipocytes: Overview …
2024年3月26日 · Here, the current knowledge of adipogenic differentiation in MSCs is reviewed, focusing on signaling pathways, noncoding RNAs and epigenetic effects on DNA methylation …
Adipose-derived mesenchymal stem cells (MSCs) are a superior …
2024年4月1日 · Among four tissues analyzed, adipose-derived MSCs are the best for bone regeneration. Transcriptomic analysis confirms multiple osteogenic pathways are activated in …
Adipokines at the crossroads of obesity and mesenchymal stem …
2023年2月7日 · In this review, we aim to discuss the current knowledge on the central role of adipokines in the crosstalk between obesity and MSC dysfunction. We also summarize recent …
Adipose-derived mesenchymal stromal cells in clinical trials: …
2024年8月15日 · Adipose tissue removed during various types of surgical procedures is a rich source of MSCs (AD-MSCs) and these cells can be stimulated in vitro to form adipocytes, …
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