Lipid metabolism and cancer - PubMed
2021年1月4日 · Cancer cells harness lipid metabolism to obtain energy, components for biological membranes, and signaling molecules needed for proliferation, survival, invasion, metastasis, and response to the tumor micr …
Lipid metabolism in cancer: A systematic review - PMC
Understanding the genes and pathways most commonly involved in lipid metabolism in cancer could help provide evidence for elucidating the mechanisms of cancer cell death and potentially help in the discovery of potential cancer therapeutic targets.
Lipid metabolism in cancer - PubMed
Changes in lipid metabolism can affect numerous cellular processes, including cell growth, proliferation, differentiation and motility. This review will examine some of the alterations in lipid metabolism that have been reported in cancer, at both cellular and organismal levels, and discuss how they contribute to different aspects of ...
Lipid metabolism in cancer: New perspectives and emerging ... - PubMed
2021年5月17日 · An increased focus on cancer lipid metabolism has unveiled a number of mechanisms that promote tumor growth and survival, many of which are independent of classical cellular bioenergetics. These mechanisms include modulation of ferroptotic-mediated cell death, support during tumor metastasis, and interactions with the cells of the tumor ...
Lipid metabolic reprogramming in cancer cells | Oncogenesis
2016年1月25日 · A simplified map of the main altered lipid metabolic pathways in cancer cells. Lipid metabolic network (blue) includes import/export and catabolic pathways (FAO) as well as de novo...
Lipid metabolism in cancer: New perspectives and emerging …
2021年5月17日 · Lipid metabolism is often drastically altered in cells undergoing transformation to a malignant phenotype. Tumor cells can increase de novo lipogenesis, fatty acid (FA) uptake, and FA oxidation (FAO) for energy production and lipid accumulation.
The role of lipids in cancer progression and metastasis - Cell Press
2022年10月18日 · Increasing evidence shows that lipid metabolism is commonly enhanced at different stages of cancer development. These alterations go beyond energetically fueling tumor cells and also trigger signaling and epigenetic events, as well as changes in membrane composition that favor metastasis (Broadfield et al., 2021a).
Lipid metabolism in cancer: New perspectives and emerging ... - Cell …
Lipid metabolism is often drastically altered in cells undergoing transformation to a malignant phenotype. Tumor cells can increase de novo lipogenesis, fatty acid (FA) uptake, and FA oxidation (FAO) for energy production and lipid accumulation.
Lipid metabolism in cancer cells under metabolic stress
2019年5月16日 · In this article, we provide an overview of recent insights into the regulation of lipid metabolism in cancer cells under metabolic stress and discuss how this metabolic adaptation helps cancer...
How cancer cells remodel lipid metabolism: strategies targeting ...
2021年11月14日 · Reprogramming of lipid metabolism has received increasing recognition as a hallmark of cancer cells because lipid dysregulation and the alteration of related enzyme profiles are closely correlated with oncogenic signals and malignant phenotypes, such as metastasis and therapeutic resistance.
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