Chromosomal inversion - Wikipedia
Inversions can also be essential in the origination of new sex chromosomes. They can cause linkage disequilibrium between a sex-determining mutation and sex-antagonistic loci and create a new sex chromosome from an autosome.
Pericentric inversions of chromosome 4: report of a new family …
So as to analyze the occurrence of recombinants, the cytogenetic data from this family are compared with those of the 18 previously reported familial cases of pericentric inversions (PIs) of chromosome 4.
染色体倒位 - 百度百科
染色体倒位(inversion)是由于同一条染色体上发生了两次断裂，产生的片段颠倒180度后重新连接造成的。 如果倒位发生在染色体的一条臂上，称为臂内倒位(paracentric)；如果倒位包含了着丝粒区，则称为臂间倒位(pericentric)。
Chromosome 4 - Wikipedia
Chromosome 4 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 4 spans more than 190 million base pairs (the building material of DNA) and represents between 6 and 6.5 percent of the total DNA in cells.
Recombinant Chromosome 4 from a Familial Pericentric Inversion ...
2013年5月16日 · Pericentric inversion of chromosome 4 can give rise to recombinant chromosomes by duplication or deletion of 4p. We report on a familial case of Wolf-Hirschhorn Syndrome characterized by GTG-banding karyotypes, FISH, and array CGH analysis, caused by a recombinant chromosome 4 with terminal 4p16.3 deletion and terminal 4q35.2 duplication.
Inversion variants in the human genome: role in disease and …
2010年2月12日 · The best-studied examples are two inversions located on chromosomes 4 and 8, respectively. Both these inversions have breakpoints that fall in clusters of olfactory receptors of high identity.
Eco-Evolutionary Genomics of Chromosomal Inversions
2018年6月1日 · Inversions were first discovered during the early 1920s by Alfred Sturtevant while comparing the genetic maps of closely related Drosophila spp. [2]. He postulated that inversions segregate as distinct units by showing that they reduce the …
Translocations, inversions and other chromosome rearrangements
Paracentric inversions occur in one arm of the chromosome and do not include the centromere . Unbalanced paracentric inversions produce gametes that have either no centromere (acentric) or two centromeres (dicentric) and are thus not viable.
Chromosome Inversions Inversions are probably the most common type of chromosome aberrations found in natural animal and plant populations (Darlington, 1937; Dobzhansky, 1941).
Testing the evolutionary theory of inversion polymorphisms in the ...
2024年11月29日 · We also find two cases of nested inversion: inv_6a/inv_6b (chromosome 1) and inv_10a/inv_10b (chromosome 2). For each, two alternative lines exhibit inversions from the reference genome within the ...