Glycogen debranching enzyme - Wikipedia
The human glycogen debranching enzyme (gene: AGL) is a monomer with a molecular weight of 175 kDa. It has been shown that the two catalytic actions of AGL can function independently of …
15.3: Glycogenolysis and its Regulation by Glucagon and …
Two key enzymes are required for the stepwise catabolism of glycogen, glycogen phosphorylase, and glycogen debranching enzyme. In the liver, the ultimate end product is glucose-1 …
Crystal structure of glycogen debranching enzyme and insights …
2016年4月18日 · Glycogen is a branched glucose polymer and serves as an important energy store. Its debranching is a critical step in its mobilization. In animals and fungi, the 170 kDa …
Biochemistry, Glycogenolysis - StatPearls - NCBI Bookshelf
2024年1月9日 · The glycogen debranching enzyme is one of the few known proteins possessing 2 independent catalytic activities that occur at separate sites on a single polypeptide chain. …
Crystal structure of glycogen debranching enzyme and insights …
Debranching of glycogen is an important step in its use as an energy source. Here, the authors describe the crystal structures of glycogen debranching enzyme alone and in complex with …
Biochemistry, Glycogen - StatPearls - NCBI Bookshelf
2023年5月1日 · Glycogen branching is essential because it allows for increased water solubility and several sites to break it down; this allows for easy and quick glycogen utilization when it is …
Glycogen Debranching Enzyme - an overview - ScienceDirect
Glycogen-debranching enzyme plays an important role in the degradation of glycogen and has two independent catalytic activities, oligo-1,4→1,4-glucanotransferase and amylo-1,6 …
Glycogen Debranching Enzyme - an overview - ScienceDirect
Glycogen debranching enzyme catalyzes the removal of α- (1→6)-linked maltotetraosyl branch points in limit dextrin (glycogen degraded extensively by glycogen phosphorylase alone) …
Clinical, biochemical and genetic features of glycogen debranching ...
Debranching enzyme is a single 1532 aminoacid chain weighing about 165 kDa and consisting of two independent catalytic activities: oligo-1,4-1,4-glucantransferase [EC 2.4.1.25] and amylo …
Glycogen Debranching Enzyme - an overview - ScienceDirect
Glycogen debranching enzyme is deficient and glycogenolysis stops when the enzyme glycogen phosphorylase encounters a branch point that is four glucose residues away. Four subtypes …