Chloroquine: Uses, Interactions, Mechanism of Action - DrugBank …
Chloroquine is an antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
Chloroquine - Wikipedia
Chloroquine is an antiparasitic medication that treats malaria. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. ... Chloroquine comes in tablet form as the phosphate, sulfate, and hydrochloride salts. Chloroquine is usually dispensed as the phosphate. [57] Names. Brand names include ...
Chloroquine Hydrochloride | C18H28Cl3N3 | CID 83820 - PubChem
Chloroquine Hydrochloride is the hydrochloride salt of chloroquine, a synthetic quinoline with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum.
Chloroquine Uses, Side Effects & Warnings - Drugs.com
2023年8月3日 · Chloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Chloroquine is not effective against all strains of malaria, or against malaria in areas where the infection has been resistant to a similar drug called hydroxychloroquine.
Mechanisms of action of hydroxychloroquine and chloroquine ...
2020年2月7日 · Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other...
Chloroquine: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月17日 · Treatment, acute attack, uncomplicated: Infants, Children, and Adolescents: Oral: Initial 16.6 mg/kg chloroquine phosphate (maximum initial dose: 1,000 mg chloroquine phosphate); followed by 8.3 mg/kg chloroquine phosphate (maximum dose: 500 mg chloroquine phosphate/dose) administered at 6, 24, and 48 hours after initial dose for a total of 4 ...
Chloroquine (oral route) - Mayo Clinic
2024年2月1日 · Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work (resistance).
Chloroquine hydrochloride - DrugBank Online
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17 Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of ...
Chloroquine (Aralen) | Davis’s Drug Guide
Doses below expressed as chloroquine base: 1 mg of chloroquine base = 1.67 mg chloroquine phosphate or 1.25 mg chloroquine hydrochloride. Suppression/Prophylaxis of Malaria. PO (Adults): 300 mg once weekly, starting 2 wk prior to entering endemic areas and for 8 wk afterward. If suppressive therapy is not initiated prior to entering endemic ...
Chloroquine | Description, Uses, & Side Effects | Britannica
Chloroquine is administered orally as chloroquine phosphate. It also can be given by intramuscular injection as chloroquine hydrochloride. Chloroquine is effective against susceptible strains of the malarial parasites Plasmodium vivax , P. ovale , and P. falciparum as well as certain parasitic worms and amoebas .