Older children and adults typically have involvement of the flexor surfaces (antecubital and popliteal fossa), neck, wrists and ankles .

This person has inherited allergic skin inflammation (atopic dermatitis) on the arms. Red (erythematous), scaly plaques can be seen on the inside of the elbows (antecubital fossa). In adults, atopic dermatitis usually involves the body creases, or flexural areas (antecubital fossa and popliteal fossa).

It favors the antecubital/popliteal fossae, neck, wrists, umbilical area, and eyelids. Similar to PR, the darker the patient’s skin, the more likely the rash is to be dark.

This 28-year-old woman presented with a 2-month history of a rash that was confined to her right antecubital fossa and that had a burning sensation. Her medical history is complicated by a several-month history of interstitial pneumonitis that was being treated with azathioprine and a tapering dose of prednisone (now down to 10 mg daily).

A skin condition called neurodermatitis (lichen simplex chronicus) starts with a patch of itchy skin. You scratch the area, which provides only temporary relief. Scratching actually makes the skin itchier because it activates the nerve fibers in your skin. Over time, you may scratch out of habit.