cAMP-dependent pathway - Wikipedia
Learn about the molecular biology of cAMP, a secondary messenger that mediates cell communication through G protein-coupled receptors. Find out how cAMP is activated, deactivated, and involved in various cell responses and processes.
Cyclic adenosine monophosphate - Wikipedia
Cyclic adenosine monophosphate (cAMP) is a second messenger that conveys the effects of hormones and other signaling molecules in cells. Learn about its synthesis, functions, and role in eukaryotic cells, especially in protein kinase A activation.
Biochemistry, cAMP - StatPearls - NCBI Bookshelf
2023年7月25日 · cAMP-PKA signaling is involved in regulation of spinal HCN channels function in diabetic neuropathic pain. [Neurosci Lett. 2021] Ma Y, Chen J, Yu D, Wei B, Jin H, Zeng J, Liu X. Neurosci Lett. 2021 Apr 17; 750:135763.
The cAMP Signal Transduction Pathway | Science Signaling
2010年4月27日 · This resource provides and describes two animated lessons that illustrate the adenosine 3′,5′-monophosphate (cAMP) signal transduction pathway. They are designed for any collegiate-level course that presents the basic steps of the prototypical pathway.
cAMP Signaling - an overview | ScienceDirect Topics
cAMP signaling refers to the process in which extracellular ligands activate G protein-coupled receptors, leading to the synthesis of cAMP by adenylyl cyclases. cAMP then activates various effectors such as protein kinase A, cyclic nucleotide-gated channels, and POPDC proteins.
Local cAMP signaling in disease at a glance - PMC
A burgeoning knowledge of compartmentalized cAMP signaling is revealing how the local control of signaling enzyme activity impacts upon disease. The aim of this Cell Science at a Glance article and the accompanying poster is to highlight how misregulation of local cyclic AMP signaling can have pathophysiological consequences.
cAMP Signaling - an overview | ScienceDirect Topics
cAMP signaling is an evolutionarily conserved intracellular communication system controlling numerous cellular functions. Until recently, transmembrane adenylyl cyclase (tmAC) was considered the major source for cAMP in the cell, and the role of cAMP signaling was therefore attributed exclusively to the activity of this family of enzymes.
Sensitive genetically encoded sensors for population and …
2022年10月27日 · Cyclic adenosine monophosphate (cAMP) signaling integrates information from diverse G-protein-coupled receptors, such as neuromodulator receptors, to regulate pivotal...
cAMP signaling: a remarkably regional affair - Cell Press
RAINs contain universal signaling proteins of the GPCR/cAMP signaling axis such as G proteins, ACs, PKA and its substrates, and PDEs. What drives the formation of RAINs, or do preformed RAINs exist under basal conditions? How is specificity in GPCR signaling encoded given the common set of signaling proteins inside RAINs? What modulates RAIN ...
GPCR activation controls local cAMP synthesis and localized cAMP signaling in receptor-associated independent cAMP nanodomains (RAINs). Further, downstream cAMP-driven protein kinase A (PKA) signaling is also