Virulence factor - Wikipedia
The factors are used to assist and promote colonization of the host. These factors include adhesins, invasins, and antiphagocytic factors. Bacterial flagella that give motility are included in these virulence factors. [5] The factors, including toxins, …
[Phagocytosis and the antiphagocytic factors in mycobacterial ...
A characteristic is given to antiphagocytic factors which permit some species of mycobacteria to avoid protective bactericidal reactions of mammals and to reproduce in phagocytes. Expression of mycobacterial virulence depends on the character of interrelations between the pathogen and cells of reticuloendothelial and immune systems.
15.3 Virulence Factors of Bacterial and Viral Pathogens
Some bacteria can cause shock through the release of toxins (virulence factors that can cause tissue damage) and lead to low blood pressure. Gram-negative bacteria are engulfed by immune system phagocytes, which then release tumor necrosis factor, a …
Virulence factors of bacteria; microbial virulence factors
2018年2月24日 · 2. Antiphagocytic factors: Once microorganism enters the body, it is immediately killed by Phagocytic cells of host. In order to survive and cause disease microorganism must resist killing by phagocytosis. Capsule is an important antiphagocytic factor for some bacteria.
Bacterial avoidance of phagocytosis - ScienceDirect
2002年5月1日 · In this review, we focus on some bacterial pathogens, the antiphagocytic properties of which have been characterized at the molecular level, and discuss the strategies and mechanisms these bacteria use to escape phagocytosis.
The pH 6 Antigen Is an Antiphagocytic Factor Produced by
The F1 capsular antigen is well known to be an antiphagocytic factor of Y. pestis (6, 12). In order to investigate if F1 antigen was a factor in the observed antiphagocytosis in these experiments (Fig. (Fig.1), 1), the bacteria used for infection of
Unraveling the molecular determinants of the anti-phagocytic …
2022年3月31日 · Here, we demonstrate that the anti-phagocytic activity of F1 is dependent on three factors: its low affinity for cells in general, its lack of specific ligands for critical macrophage receptors and its high mechanical stability.
Antiphagocytic factors of Staphylococcus aureus - ScienceDirect
1980年1月1日 · Several staphylococcal substances could interfere with phagocytosis, imparting a definite advantage on Staphylococcus aureus in the initial phase of infection. Leukocidins were shown to damage mainly granulocytes and macrophages. Clumping-factor, by direct reaction with fibrinogen, induced clumping of the staphylococci in plasma.
Control of Phagocytosis by Microbial Pathogens - PMC
Phagocytosis involves a series of steps from recognition of the target particle, ingestion of it in a phagosome (phagocytic vacuole), maturation of this phagosome into a phagolysosome, to the final destruction of the ingested particle in the robust antimicrobial environment of the phagolysosome.
Role of Phagocytosis in the Virulence of Cryptococcus neoformans
The production of antiphagocytic factors, such as the polysaccharide capsule and App1 of C. neoformans, could be the evolutionary result of this interaction. Thus, studies addressing the cross talk between environmental fungi and protozoa may provide significant insights into the molecular mechanisms by which fungi adapted and became virulent ...