α-Glucosidase - Wikipedia
α-Glucosidase (EC 3.2.1.20, (systematic name α-D-glucoside glucohydrolase) is a glucosidase located in the brush border of the small intestine that acts upon α (1→4) bonds: …
α-Glucosidases and α-1,4-glucan lyases: structures, functions, and ...
2016年4月30日 · α-Glucosidases (AGases) and α-1,4-glucan lyases (GLases) catalyze the degradation of α-glucosidic linkages at the non-reducing ends of substrates to release α …
Acid alpha-glucosidase - Wikipedia
Acid alpha-glucosidase, also called acid maltase, [5] is an enzyme that helps to break down glycogen in the lysosome. It is functionally similar to glycogen debranching enzyme, but is on …
α-Glucosidases and α-1,4-glucan lyases: structures ... - PubMed
α-Glucosidases (AGases) and α-1,4-glucan lyases (GLases) catalyze the degradation of α-glucosidic linkages at the non-reducing ends of substrates to release α-glucose and …
Glucan 1,4-α-glucosidase - Wikipedia
Glucan 1,4-α-glucosidase (EC 3.2.1.3, glucoamylase, amyloglucosidase', γ-amylase, lysosomal α-glucosidase, acid maltase, exo-1,4-α-glucosidase, glucose amylase, γ-1,4-glucan …
Glucan 1,4 Alpha Glucosidase - an overview - ScienceDirect
Acid alpha-glucosidase has α-1,4- and α-1,6-glucosidase activities. These activities promote hydrolysis of glycogen to glucose, and absence of these enzymes results in glycogen …
Structure of human lysosomal acid α-glucosidase–a guide for …
2017年10月24日 · Moreland, R. J. et al. Lysosomal acid alpha-glucosidase consists of four different peptides processed from a single chain precursor. J. Biol. Chem. 280, 6780–6791 …
Glucan 1,4 Alpha Glucosidase - an overview - ScienceDirect
Glucan 1,4 Alpha Glucosidase is an enzyme that functions as an exohydrolase by cleaving limit dextrins from one end, liberating glucose residues from the substrate during glucose …
Alpha-Glucosidase - an overview | ScienceDirect Topics
Alpha-glucosidase is an enzyme that plays an important role in the absorption of glucose in the gastrointestinal tract. Inhibition of this enzyme activity can reduce blood glucose levels, …
Lysosomal acid alpha-glucosidase deficiency (Pompe disease ... - UpToDate
2024年1月23日 · GAA deficiency is an autosomal-recessive disorder with considerable allelic heterogeneity. It is caused by pathogenic variants in the gene encoding lysosomal acid alpha …
Glycogen Storage Diseases Types I-VII - Medscape
2022年12月1日 · Alpha-1,4-glucosidase acts hydrolyzing the alpha 1,4 and 1,6 glucosidic linkages of the glycogen molecule within the lysosome, hence, causes its degradation. In the …
Glucan 1,4-alpha-glucosidase (EC 3.2.1.3) | Protein Target
2020年2月1日 · Description. Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this …
Linking Diabetes to Alzheimer’s Disease: Potential Roles of Glucose ...
Alpha-glucosidase is a critical enzyme which regulates blood glucose by specifically targeting 1,4-α-glucopyranosidic bonds and subsequently hydrolysing them to produce α-glucose . …
Alpha Glucosidase - an overview | ScienceDirect Topics
1999年5月4日 · Alpha-glucosidase is an enzyme that is inhibited by certain medications to prevent the breakdown of complex carbohydrates into glucose in the small intestine, leading to …
Alglucosidase alfa - DrugBank Online
Alglucosidase alfa is an acid alpha- glucosidase (GAA) derivative used as an enzyme replacement therapy for the treatment of Pompe disease in infants and pediatric patients …
acid alpha glucosidase vs glycogen phosphorylase
2018年6月20日 · Acid alpha glucosidase (sometimes called α-1,4-glucosidase or acid maltase) is not among those enzymes involved the pathways of glycogen synthesis and breakdown.
Pompe disease - MedlinePlus
The GAA gene provides instructions for producing an enzyme called acid alpha-glucosidase (also known as acid maltase). This enzyme is active in lysosomes, which are structures that serve …
Glucan 1,4 Alpha Glucosidase - an overview - ScienceDirect
α-Glucosidase (EC 3.2.1.20), or α-d-glucoside glucohydrolase, attacks the α-1,4 linkages of oligosaccharides. Unlike glucoamylase, which produces glucose with β-anomeric …
Glucosidase acid-1,4-alpha deficiency | About the Disease | GARD
Glucosidase acid-1,4-alpha deficiency, also known as Pompe disease, is classified by age of onset, organ involvement, severity, and rate of progression.
Glucan 1,4 Alpha Glucosidase - an overview - ScienceDirect
Genetic deficiency of acid α-1,4 glucosidase, an enzyme involved in the breakdown of glycogen to glucose, results in a wide clinical spectrum ranging from the rapidly fatal infantile onset of type …
Glucan 1,4-alpha-Glucosidase - MeSH - NCBI - National Center …
Glucan 1,4-alpha-Glucosidase. An enzyme that catalyzes the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of polysaccharide chains with …