Biocatalysts have many benefits for speeding up specific transformations, but the chemistry used by naturally occurring catalysts is limited. Pioneering work in 2016 used directed evolution to ...
Masroor Ahmad Paddar and colleagues reveal noncanonical roles of ATG5 and membrane ATG8ylation in regulating retromer assembly and function. They identify ATG5's unique non-autophagic role and show ...
Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, United States; Department of Molecular Genetics & Cell Biology, University of Chicago, United States; ...
Using just 20 amino acid letters, ribosomes spell out all the proteins needed to keep cells ticking. But Jason Chin, head of Cambridge’s Centre for Chemical & Synthetic Biology, has long ...
Department of Chemical Engineering, South Kensington Campus, Imperial College London, London SW7 2AZ, U.K. Institute of Chemical Biology, Molecular Sciences Research Hub, Imperial College London, ...
: chemical structures of the nitroimidazoles: benznidazole (8), megazol (9) and a metronidazole analog (10). Several nitroimidazoles possess good oral therapeutic activity against protozoal parasites; ...