The Antigen Discovery and Molecular Biology Unit expresses and purifies recombinant protein antigens for vaccines against neglected tropical diseases and other emerging infectious diseases. The unit ...
Here, Jeffrey Almond discusses the selection of articles in this Focus ... Their ultimate goal is epitope engineering of important vaccine antigens, although the feasibility of this for large ...
Several observations point toward the possibility of a vaccine development strategy ... of most of these surface proteins has made antigen selection problematic. Obstacles to the development ...
The approach builds off the current bivalent Human Hookworm Vaccine now in clinical development and would ultimately add both a larval Ascaris lumbricoides antigen and an adult-stage Trichuris ...
The product line includes Neuraminidase (NA), Hemagglutinin (HA) and Nucleoprotein (NP) proteins, from all WHO-recommended vaccine strains in the past few years. Such antigens could be utilized to ...
AI-Immunology™ can select ERV antigens for precision therapeutic cancer vaccines, offering therapeutic options for multiple specific cancer types and potentially enabling treatment for patients ...
While RNA vaccines are being evaluated in clinical trials, current practice of antigen selection is based on the predicted stability of antigens on the surface of tumor cells. "It's not so black ...