Moreover, if combinations with antitumor vaccines are to be considered ... such as participant selection, number of antigens chosen for prioritization, errors in rank order, multicollinearity ...

Immune checkpoint blockade (ICB) therapies can be very effective against some cancers by helping the immune system recognize ...

Delve into the expanding and diverse field of cancer vaccines with various approaches exploiting the immune system to fight ...

Fourteen of 18 patients had neoantigen-specific T-cell responses; recurrence-free survival was 87.5 percent at 36 months.

Selection of 19 individual researchers among ... Cheever and colleagues establish a definition of 'ideal' antitumor vaccine antigens based on weighted criteria, including: evidence of antitumor ...

Global Affairs Canada, and Bill & Melinda Gates Foundation called on scientists to create vaccines for neglected livestock ...

Final antigen selection will apply a ranking system that includes the ... The partnership is currently identifying novel vaccine antigen candidates for all three soil-transmitted helminths. Using ...

Focusing on a limited set of antigens is also relevant to cancer ... the most precise selection of vaccine components exists in epitope-based peptide vaccines, which are the subject of this ...

Here, Jeffrey Almond discusses the selection of articles in this Focus ... Their ultimate goal is epitope engineering of important vaccine antigens, although the feasibility of this for large ...

Immune responses targeting selected neoantigens were identified in 100% of patients who received TG4050, demonstrating the strong immunogenicity of the cancer vaccine, with both de novo and ...