Selection of 19 individual researchers among ... Cheever and colleagues establish a definition of 'ideal' antitumor vaccine antigens based on weighted criteria, including: evidence of antitumor ...
Delve into the expanding and diverse field of cancer vaccines with various approaches exploiting the immune system to fight ...
Their combined expertise in antigen selection, design and testing provided a pipeline of new and original vaccine antigens to select from. "Developing a new vaccine was based on foundational ...
Immune checkpoint blockade (ICB) therapies can be very effective against some cancers by helping the immune system recognize ...
Final antigen selection will apply a ranking system that includes the ... The partnership is currently identifying novel vaccine antigen candidates for all three soil-transmitted helminths. Using ...
Focusing on a limited set of antigens is also relevant to cancer ... the most precise selection of vaccine components exists in epitope-based peptide vaccines, which are the subject of this ...
Here, Jeffrey Almond discusses the selection of articles in this Focus ... Their ultimate goal is epitope engineering of important vaccine antigens, although the feasibility of this for large ...
Several observations point toward the possibility of a vaccine development strategy ... of most of these surface proteins has made antigen selection problematic. Obstacles to the development ...
Immune responses targeting selected neoantigens were identified in 100% of patients who received TG4050, demonstrating the strong immunogenicity of the cancer vaccine, with both de novo and ...