McClintock also saw that telomeres prevent these kinds of fusion events from occurring. Despite the magnitude of these discoveries, 40 years would elapse between McClintock's original observations ...

Telomeres are specialized nucleoprotein structures at the ends of eukaryotic chromosomes that are essential for chromosome stability and cellular proliferation. Telomeric DNA does not encode for ...

Telomerase is an enzyme that can compensate for this shortening by maintaining telomeres at a stable length, helping to protect chromosomes against degradation and fusion. Mutations that ...

It is commonly understood that DNA damage is largely sensed and repaired in interphase and it is proposed that DNA repair is largely repressed during mitosis due to the risk of telomere fusion. Cancer ...

Telomeres are present at both ends of chromosomes, thereby protecting them from degradation and fusion with other chromosomes to preserve genetic information. Between 50-100 base pairs of ...