Telomeres are specialized nucleoprotein structures at the ends of eukaryotic chromosomes that are essential for chromosome stability and cellular proliferation. Telomeric DNA does not encode for ...
Telomere Biology Is an Active Area of Research Our view of the telomere has matured considerably since Blackburn and Gall provided the first information about its molecular composition.
The Arnoult lab focuses on genome stability, DNA repair and telomere biology. We study the different types of pathways that cells use to repair DNA double strand breaks, and how telomeres escape these ...
Implications for Aging Research This study's findings challenge the traditional view of telomere biology and aging. Instead of a uniform shortening of telomeres across all chromosomes, we now know ...
The starting point for the project is a reconstituted system for DNA replication that we have recently developed in the Telomere Biology lab. Combining this system with chromatinised DNA templates and ...
Telomeres are nucleoprotein caps that protect the ends of eukaryotic chromosomes from repair processes and DNA damage. Each cell cycle, these complex, dynamic structures are copied and reassembled ...
We are entering into an exciting era of genomics where truly complete, high-quality assemblies of human chromosomes are available end-to-end, or from ‘telomere-to-telomere’ (T2T). Recently, the ...
HBOT has been shown to reduce the presence of senescent cells by 37%, offering a unique pathway for rejuvenating tissues, ...