With a single B cell screening platform ... “Integrated with single cell sequencing technology, the target antibody sequences can be easily obtained. This reduces the cycle of the whole process ...

The Cyto-Mine ® platform by Sphere Fluidics utilizes innovative picodroplet-based technology to capture and screen antibodies directly from entire B cell repertoires, maintaining cell viability ...

A few years ago, her research group used single ... so that antibodies can reach their targets inside the cell. Crucially, this method still leaves mRNA available for sequencing.

A Golden Gate-based dual-expression vector enables rapid screening, which facilitates efficient isolation of high-affinity cross-reactive antibodies for therapeutic or diagnostic use and provides a ...

Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...