Dinsmore and colleagues investigated the efficacy and safety of topical eutectic lidocaine–prilocaine mixture for premature ejaculation (TEMPE), applied to the glans penis via a metered-dose ...

An eutectic mixture of lidocaine 2.5% and prilocaine hydrochloride 2.5%, commonly known as EMLA® (Astra, Westborough, MA) cream, has also been widely used for local anesthesia during the procedure.