Orexin, also known as hypocretin, is a brain hormone that helps regulate sleep. A deficiency of this hormone can cause a person to develop type 1 narcolepsy. Type 1 narcolepsy, formerly known as ...
Orexin antagonists, meanwhile – such as Eisai's Dayvigo (lemborexant), Merck & Co's Belsomra (suvorexant) and Idorsia's recently filed daridorexant – have proved effective as treatments for ...
Idorsia has become the first drugmaker in the EU to claim approval for a drug for chronic insomnia in the dual orexin receptor antagonist class, ahead of rival drugs from Merck & Co and Eisai.
The European Patent Office will issue a formal grant for TheraCryf's drug, the 'Ox-1' receptor anatagonist, on December 18. The drug was developed by British biotech firm Chronos Therapeutics Ltd, ...