Many of the nucleoside antibiotics exhibit their activity only after conversion into their nucleotide form (mono- or triphosphate) once inside the cell. A number of nucleoside analogues which were ...

The main goals of chronic hepatitis B treatment should be the long-term suppression of viral replication to minimize disease progression and the risk for the development of hepatocellular carcinoma.

(A) Nucleoside triphosphates serve as a substrate ... releases the free energy needed to drive the incorporation of each nucleotide into the growing DNA chain. The reaction shown on the bottom ...

Initial regimens composed of an integrase strand transfer inhibitor, specifically bictegravir or dolutegravir, with one or ...

Xalnesiran plus an immunomodulator results in a substantial percentage of patients with hepatitis B surface antigen (HBsAg) loss.