Candesartan (CHARM-P) 3023 EF >40%; mean age: 67; NYHA class II–IV ... Heart failure normal ejection fraction (HFNEF) is growing at an alarming rate and has a complex pathophysiology.
Several epidemiological studies confirm that the prevalence of heart failure with normal ejection fraction is increasing. Given the current trends, heart failure with normal ejection fraction will ...
symptoms of NYHA class 3–4 heart failure, and low ejection fraction associated with mild left ventricular dilation, among other signs of heart dysfunction. Transmission electron micrographs of ...
The main outcome measures are cardiovascular death and the change from baseline in NYHA classification, left ventricular ejection fraction (LVEF), peak oxygen (VO2), and six-minute walk test ...
Factors portending the greatest risk for cardiovascular death in control patients were inflammation (baseline plasma high-sensitivity C-reactive protein =2 mg/L; p=0.003) and ischemic HFrEF etiology ...