This is an important study using a combination of optogenetics and calcium imaging to provide insight into the function of the cholinergic input to the prelimbic cortex in probabilistic spatial ...

"and how the brain's executive function helps us decide when to wait or walk away." The research looks at individuals with damage to different parts of the prefrontal cortex, the seat of executive ...

Corticotropin-releasing factor (CRF) neuron activity in the medial prefrontal cortex (mPFC) specifically modulates the influence of affective past experience on emotional reactions to others ...

Both tests evaluate the ability to remember and discriminate between new and familiar stimuli—a function closely tied to medial prefrontal cortex activity. Mice exposed to either drug displayed ...