The mast cells in mastocytosis accumulate in tissues that generally release more mediators (histamine, cytokines, and proteases). The number of basophils, which can react like mast cells ...

Mediators of mast cells and basophils provoke interest as potential markers of anaphylactic reactions that may be useful both in the diagnosis of venom allergy and monitoring venom immunotherapy.

Aim: To evaluate markers of mast cell and basophil activation in children undergoing the initial phase of honeybee venom immunotherapy (VIT). Patients & methods: Five children (four boys and one ...