The factors underlying accelerated atherosclerosis in diabetes extend beyond dyslipidemia, hypertension and obesity. Even after correction of these typical risk factors, patients with diabetes ...

that is strongly correlated with atherosclerosis. Macrophages mediate a limited-specificity immune response that includes recognition of ‘foreign’ lipid derivatives. Macrophages display a ...

A recent study by researchers from Fudan University and Tau Cambridge Ltd. explored a novel therapeutic strategy that combines targeting CD47 with ANGPTL3, a key regulator of lipid metabolism, as a ...

New research from Salk Institute scientists describes how another class of lipids, called sphingolipids ... Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to ...

Several mechanisms have been proposed to explain the dyslipidemia seen with both HIV infection and exposure to ART. The principal dyslipidemia induced by HIV infection is low HDL-cholesterol, with ...

[113] On the other hand, advanced grades of atherosclerosis may be detected by the third decade in patients who have multiple risk factors or who present with high lipid concentrations; so ...

New research from Salk Institute scientists describes how another class of lipids, called sphingolipids ... The findings, published in Cell Metabolism on November 14, 2024, open an entirely ...

In the realm of lipid metabolism and cardiovascular diseases ... fostering reverse cholesterol transport, and decreasing the progression of atherosclerosis. Despite these encouraging findings, the ...

Blood Sugar Control: Keeping HbA1c levels below 7 per cent minimizes vascular damage and reduces the risk of complications.

New research from Salk Institute scientists describes how another class of lipids, called sphingolipids ... to trans-fat-induced atherosclerosis, Cell Metabolism (2024). DOI: 10.1016/j.cmet.