The future: relating molecular interactions to lipid structure What is an accessible goal for future studies of real and model biological membranes? Chemists place great value on having predictive ...

The hydrophilic head is composed of a choline structure (blue) and a phosphate (orange). This head is connected to a glycerol (green) with two hydrophobic tails (purple) called fatty acids.

We found that the A3 reaction was not only efficient but also flexible enough to allow for precise control over the lipids’ molecular structure.” Michael J. Mitchell, Associate Professor ...

Led by Michael J. Mitchell, associate professor in bioengineering, the researchers refined this delivery process by optimizing the structure of ionizable lipids. Moving beyond existing methods limited ...

But by using Berndsen’s electron density maps to guide molecular dynamics simulations, Cassidy could resolve the protein’s ...

"We found that the A 3 reaction was not only efficient, but also flexible enough to allow for precise control over the lipids' molecular structure," says Mitchell. This flexibility was key to fine ...

The second is based on the development of lipid anticancer agents whose molecular structures are derived from or inspired by the marine environment. Dietary factors can thus influence cancer ...

These structures revealed distinct binding ... More information: Jiuyin Xu et al, Molecular basis of lipid and ligand regulation of prostaglandin receptor DP2, Proceedings of the National Academy ...