Our approach to organoid culture and differentiation involves the use of synthetic matrices to direct morphogenesis through tunable biochemical and mechanical signals. We spatiotemporally pattern ...

Advances in three-dimensional organoid technology have revolutionized the stem cell field. Intestinal stem cells can be expanded and functionally differentiated to form “mini-organs” or organoids that ...

A single human intestinal organoid, or HIO -- a hollow ball of cells grown from human embryonic stem cells and coaxed to become gut-lining cells. Scientists can use it to study basic gut ...

Two fluorescent microscopy images of intestinal organoids growing in synthetic hydrogels. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!

Intestinal organoids vary in shape and size depending on their stage of development and their complexity. They can range from 200 micrometers at their smallest, or roughly 2.5 times larger than the ...

This event will delve into the exciting intersection of the organoid and parasitology fields, featuring thought-provoking talks from renowned experts: spheroids permits novel investigation of ...