Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. Scientists have employed mouse models in immunological ...
2006. Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease. Int Immunol 18:1759-69.
Humanized mouse models can help researchers develop more efficacious immuno-oncology treatments. They offer researchers the opportunity to study interactions in vivo and to decipher mechanisms of ...
Now, researchers from Juntendo University developed a humanized mice model and elucidated the role of CD8 + T cells in regulating the immune response against hiPS-CMs. Ischemic heart disease ...
Kobe University immuno-oncologist SAITO Yasuyuki and his team developed a mouse model with a humanized immune system. With this they successfully tested a new therapeutic approach in which immune ...