To investigate the pathophysiology of glycogenoses of the liver, glycerol, an endogenous precursor of glucose, was administered intravenously to eight patients and to 22 control subjects.

AQP7 mRNA levels are elevated by the decrease of insulin and adrenergic receptor activation causes the AQP7 protein to translocate to the cell surface to aid efficient release of glycerol.

In the baseline, rates of whole-body glycerol conversion to glucose, an index of systemic gluconeogenesis, and rates of renal glycerol conversion to glucose, an index of renal gluconeogenesis ...

causing the body to metabolize amino acids and triglycerides instead of glucose for energy. As a result, because of unrestrained lipolysis, serum levels of glycerol and free fatty acids increase. In ...