showed that spironolactone, a potassium-sparing diuretic, improves outcomes in patients with severe heart failure. The drug can sometimes cause life-threatening hyperkalemia, however, when used in ...

Potassium-sparing diuretics have a relatively weak natriuretic effect. Recently, spironolactone has been recommended to attenuate some of the neurohormonal effects of heart failure. The Randomized ...

In a new study, de Souza and colleagues demonstrate the potent blood pressure lowering effect of low-dose spironolactone in patients with evident resistant hypertension. This finding should have ...

Spironolactone for fluid retention. Of the diuretics that have been used for treatment of PMS, spironolactone has achieved the greatest popularity. This is largely the result of specific ...

Spironolactone is an antiandrogen drug (a type of medication that blocks the effects of androgen hormones) commonly ...