and therefore we have focused on three aspects of gene expression that are inextricably linked — transcription, chromatin and epigenetic regulation. These Milestones begin with studies in ...

Major changes in gene expression underlie changes in cell state, including cell growth and a stress-resistant state called quiescence. Our scientists study how the organization of our chromatin - the ...

This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.

cfDNA coverage shows an inverse relationship with both chromatin accessibility and gene expression levels, Using this relationship and machine learning identify patients with cancer.

Epigenetics and epigenomics represent two burgeoning fields at the forefront of modern biological inquiry. Epigenetics investigates heritable changes in gene expression that occur without any ...

Researchers unveil a comprehensive multi-omics atlas of ovarian aging, highlighting coordinated gene expression changes, mTOR ...

Healthcare - The exploration of peptides as bioregulatory molecules has gained considerable attention in recent years, with a ...

Long non-coding RNAs are RNA molecules longer than 200 nucleotides that do not encode proteins. They can regulate gene expression through various mechanisms, such as chromatin remodeling, ...

Vilon, a bioregulatory peptide, has captured the attention of scientists for its unique characteristics and intriguing ...

In this potentially valuable study, the authors employed in vivo experiments and theoretical modeling to study the growth dynamics of nuclear condensates. They observed that condensates can exhibit ...