Involuntary movements (dyskinesia) develop in the course of Parkinson's disease (PD ... with an imbalance in the output of the basal ganglia, but the pathophysiology of the involuntary movements ...

Idiopathic Parkinson’s disease (IPD) is a central nervous system disorder affecting the basal ganglia that is caused by death of dopamine-producing cells in the substantia nigra. Although IPD is ...

The substantia nigra reticulata (SNr) is a part of the basal ganglia that controls movement. During Parkinson's disease, there is an increase in SNr activity, leading to the motor impairments that ...

Parkinson's disease (PD) is a common neurodegenerative disorder ... Sometimes, a dopamine transporter scan (DaTscan) is ordered which can help show a loss of dopamine in the deeper structures of the ...

A large number of computational models of information processing in the basal ganglia have been developed in recent years. Prominent in these are actor-critic models ...

Corticobasal syndrome (CBS) is a form of atypical parkinsonism (a parkinsonism-plus syndrome), which means that it shares some features with Parkinson's disease such as slowness of movement ... as ...

The University of Pittsburgh Brain Institute is working to unlock new therapy treatment for people with Parkinson’s disease ... bottom of the brain at the basal ganglia. Strick’s research ...