氨基-二聚乙二醇-VG-N-双 (一聚乙二醇-叠氮) 是一个高度灵活的连接子分子,结合了酶敏感性、水溶性和生物正交化学功能,广泛应用于药物开发、分子标记和生物材料领域,是现代生物技术中的重要工具。
The unnatural amino acid azidohomoalanine (AHA ... The side chain of AHA contains an azide functional group which is not found in nature, but spontaneously reacts with an alkyne (another ...
The azide- and alkyne-bearing amino acids react to form a cross-link, constraining the protein structure in a locked conformation. The method could also be used to install probes for imaging and ...