During an acute attack of gout, inflammatory mediators are released and vascular adhesion and chemotaxis of leukocytes to the inflamed joint is enhanced. 7 However, for this to have an impact on ...

Systemic inhibition of interleukin (IL)-1 with rilonacept (IL-1 Trap) could be an effective therapy for the pain and inflammation associated with acute gout. As demonstrated in a novel mouse model ...

For many people, pain at the beginning of a gout attack (typically the first 24 hours) tends to be the worst. There are a ...

Chronic gout can cause joint deformities over time, leading to disability. The primary trigger for acute gout attacks is alcohol, particularly beer. Drinks high in fruit sugar (fructose ...

It's very common after surgical procedures, not necessarily on the foot or toe, but any surgical procedure that you can develop an acute gout attack. One of the primary recommendations for initial ...

Gout causes extremely painful episodes of acute inflammatory arthritis, joint damage and chronic tophaceous disease. Comorbidities are common, even though their exact relationship with ...

A 5-day course of oral prednisolone is a reasonable alternative to NSAIDs for treating patients with acute gouty arthritis. In a recent study of patients with acute gout, oral prednisolone was as ...

The European Commission has approved Novartis’ Ilaris for the treatment of patients with acute gouty arthritis who suffer frequent attacks, and whose symptoms cannot or should not be managed ...

Doctor Edward Dwyer knows gout when he sees it ... to be discussed with the patient is do we just want to treat the acute attacks or do you want to take a medication to reduce your level of ...