The drugs “are exciting because they work,” Lucy says, but there “has not been much innovation” in linker chemistry. Lucy says Siftr could make a real impact by improving spatial and ...
Adcentrx begins patient dosing in phase 1a/b study of ADRX-0405, a potential first-in-class ADC targeting STEAP1 to treat advanced solid tumours: San Diego, California Wednesday, ...
via a chemical linker. ADCs leverage the mAb's specificity for a tumor-associated antigen to achieve targeted cytotoxic drug delivery to tumor cells. Once an ADC binds to its target antigen on a t ...